The Eastgate Regional Council of Governments is directly responsible for a variety of federal, state, and local planning and project implementation programs. As the Metropolitan Planning Organization and Areawide Water Quality Management Agency for Mahoning and Trumbull Counties, and the designated Economic Development District, Eastgate continues to maintain required certifications and planning documents to qualify the region for federal and state funding.

Other major areas of responsibility include: air quality planning and air advisory day programs, State Capital Improvement Program administration for the District 6 Public Works Integrating Committee, administration of the Department of Defense Procurement Program, Intergovernmental review, administration of the regional Rideshare program, administration of the Clean Ohio Conservation & Revitalization Funds, local project sponsor for the Mahoning River Dredging Project, and administration of the Local Development District of the Appalachian Regional Commission.